Myc multimers shield stalled replication fork
http://www.wholenews.net/MYC-multimers-shield-stalled-replication-forks-from-RNA-polymerase/ky25932/ WebStudies from many laboratories over the past 20 years have shown convincingly that stalling of replication fork progression can be a dangerous genome-destabilizing event, leading …
Myc multimers shield stalled replication fork
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WebMYC dissociation from active promoters alters its interactions with proteins involved in transcription termination and RNA processing, influencing DNA repair and thus, … WebMYC multimers shield stalled replication forks from RNA polymerase MYC genes and their proteins play a central role in the emergence and development of almost all cancers.
WebMYC multimers shield stalled replication forks from RNA polymerase. Nature 2024-12-01 Journal article DOI: 10.1038/s41586-022-05469-4 Contributors ... Nuclear myosin VI … Web28 mrt. 2024 · MYC multimers shield stalled replication forks from RNA polymerase. Nature. doi: 10.1038/s41586-022-05469-4. Truongvan N, Li S, Misra M, Kuhn M, Schindelin H (2024). Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun 13, 4789. doi: 10.1038/s41467-022-32040-6.
Web23 nov. 2024 · MYC proteins also show an activity that was previously unknown ... Multimerization of MYC shields stalled replication forks from RNA polymerase. Article … WebMYC multimers accumulate on chromatin immediately adjacent to stalled replication forks and surround FANCD2, ATR and BRCA1 proteins, which are located at stalled forks 7,8 . MYC multimerization is triggered in a HUWE1 6 and ubiquitylation-dependent manner. At active promoters, MYC multimers block antisense transcription and stabilize FANCD2 ...
WebMYC multimers accumulate on chromatin immediately adjacent to stalled replication forks and surround FANCD2, ATR and BRCA1 proteins, which are located at stalled …
WebMultimerization is accompanied by a global change in the MYC interactome towards proteins involved in transcription termination and RNA processing. MYC multimers accumulate … grunwerg corkscrewWeb18 uur geleden · Personal stories form us!! Marco Foiani explains how it has been to manage big lab and one of the leading oncology institute in Milano IFOM, the FIRC… grunwerg 4022/40 carafe serving jug plasticWeb7 sep. 2024 · Multimerization of MYC shields stalled replication forks from RNA polymerase [BLISS] Oncoproteins of the MYC family drive the development of numerous … final de worlds 2022Web11 apr. 2024 · MYC multimers accumulate on chromatin immediately adjacent to stalled replication forks and surround FANCD2, ATR and BRCA1 proteins, which are located at stalled forks7,8. final disbursement account meaningWeb17 dec. 2024 · 本研究 证明了myc在转录延伸、mrna剪接或蛋白酶体抑制的干扰下,从其活性启动子中的许多结合位点 解离 并形成多聚体,通常是球形结构。多聚化伴随着myc相互 … final disbursement account shippingWeb29 nov. 2024 · 近日,德国维尔茨堡大学的研究人员在Nature上发表了一篇题为“MYC multimers shield stalled replication forks from RNA polymerase”的研究论文。该研究 … grunwells chronologyWeb23 nov. 2024 · Source: Nature AOP - November 23, 2024 Category: Research Authors: Daniel Solvie Apoorva Baluapuri Leonie Uhl Daniel Fleischhauer Theresa Endres … final disbursement account 意味