WebApr 14, 2024 · Background In mouse, it was discovered that resveratrol (Res) enhanced osteoporosis (OP) by boosting osteogenesis. Besides, Res can also have an impact on MC3T3-E1 cells, which are crucial for the control of osteogenesis and thus increase osteogenesis. Although some articles have discovered that Res enhanced autophagy to … WebFigure 1 Galangin (GLG) reduced the lipopolysaccharide (LPS)-stimulated induction of the expression of the pro form of matrix metallopeptidase 9 (pro-MMP-9) and cell migration in a rat brain astrocyte cell line (RBA-1). (A) Cells were pretreated with galangin (0.1, 1, or 10 μM) for 1 h and then incubated with 2 μg/mL LPS for 12 or 24 h.The conditioned medium …
Galangin Induces Autophagy via Deacetylation of LC3 by
WebAutophagy may represent a common cellular response to nanomaterials. In the present study, it was demonstrated that zinc oxide nanoparticle (ZON)-elicited autophagy contributes to tumor cell killing by accelerating the intracellular dissolution of ZONs and reactive oxygen species (ROS) generation. In particular, ZONs could promote Atg5 … WebJan 1, 2024 · Galangin prevents hepatocellular carcinoma through multiple anti-cancer mechanisms. •. The anti-cancer effects of galangin mainly include anti-proliferation, induction of apoptosis and autophagy, inhibition of metastasis. •. Moreover, it could protect normal cells and prevent the effects of genotoxic carcinogens. ifound fd22h
Molecules Free Full-Text The Molecular Mechanism of …
WebDec 4, 2014 · Autophagy is induced by galangin. (A) HepG2 cells transfected with GFP-LC3 were treated with different concentrations of galangin for 24 h. Fluorescence … WebJan 29, 2024 · Galangin is a known natural inducer for autophagy, in many cell types, including hepatocellular carcinoma (HCC) , colon cancer , and oesophageal carcinoma … WebJan 29, 2024 · In this study, the protective mechanisms conferred by galangin were assessed with an emphasis on the induction of autophagy and regulation of the gut microbiota using a DSS-induced UC mouse model. 2. Materials and Methods 2.1. Chemicals Galangin (purity: ≥99%) was obtained from Biopurify Phytochemicals Ltd. (Chengdu, … is string fruit better than ice fruit