WebJun 1, 2024 · Full dose CY (200 mg/kg) and ATG is the standard regimen in younger patients. • Patients over 30 years of age, may receive Flu, CY and ATG as conditioning regimen, with a lower dose of CY, to limit organ toxicity. • Current standard GvHD prophylaxis is a combination of CsA and MTX. Matched unrelated donor transplantation Web注:saa:重型再生障碍性贫血;aml:急性髓系白血病;mds:骨髓增生异常综合征;pnh:阵发性睡眠性血红蛋白尿症;all:急性淋巴细胞白血病;bu:白消安;cy:环磷酰胺:atg:抗胸腺细胞球蛋白;flu:氟达拉滨;gvhd:移植物抗宿主病;csa:环孢素a;mtx:甲氨蝶 ...
Choice of conditioning regimens for bone marrow transplantation …
WebMay 15, 2024 · A recent randomized study in AML patients aged 45–65 comparing BU-CY with FLU-BU has shown that the combination of FLU-BU significantly reduced NRM. 28 … WebObjective To retrospectively analyze the clinical outcomes of single unrelated cord blood transplantation (UCBT) in children with high risk and refractory acute myeloid leukemia (AML) . Methods Between June 2008 and December 2024, a total of 160 consecutive pediatric patients with AML received single UCBT (excluding acute promyelocytic … trail running shoe sail
Hematopoietic Cell Transplantation with Cryopreserved Grafts for …
WebOct 3, 2005 · In some centers, busulfan 16 or low-dose TBI 2 has been added to CY to reduce graft failure; in other centers, ATG has been used successfully to reduce graft rejection. 17 In the present series of ... WebJul 17, 2014 · Slavin et al reported a regimen incorporating fludarabine, oral busulfan (8 mg/kg), and anti-thymocyte globulin (ATG) in 26 younger … WebBusulfan was changed to Cyclophosphamide 60 mg/kg x 2 days from 2004 (Flu/Cy) and low dose ATG was stopped subsequently. In a few patients with active infection at the time of SCT, other regimens were used including Fludarabine 90 mg/m2 with TBI 200 Cgy, Fludarabine 180 mg/m2 over 6 days alone or Cyclophosphamide with Fludarabine … trail running shoe review