Cisplatin and apoptosis
WebMar 15, 2024 · Cell viability and proliferation were detected by counting kit 8 (CCK-8) and 5-ethynyl-2'-deoxyuridine (EdU) assays respectively. Apoptosis and cell cycle were analyzed by flow cytometry. The results indicated that URI knockdown increased the sensitivity of cells to cisplatin by inhibiting proliferation and promoting apoptosis. WebDec 12, 2024 · Our results show that administration of AAV-PSTPIP2 or epithelial cell-specific overexpression of PSTPIP2 reduces cisplatin-induced kidney dysfunction and inhibits apoptosis of renal tubular...
Cisplatin and apoptosis
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WebJan 29, 2024 · Apoptosis and necroptosis were previously reported to be the major pathological processes of acute kidney injury, however, preclinical works using specific inhibitor of neither apoptosis or... WebFeb 13, 2024 · Scutellarin is a active flavone extracted from Erigeron breviscapus Hand-Mazz that has been shown to exhibit anticancer activities on various types of tumors. …
WebThe cardiotoxic effect of chemotherapeutic agents as cisplatin has become a major issue recently. Interference with mitochondrial dynamics, biogenesis, redox status, and apoptosis are the most possible underlying mechanisms. Semaglutide is a human glucagon-like peptide-1 receptor agonist (GLP-1R), w …
WebCisplatin is a type of chemotherapy. It destroys quickly dividing cells, such as cancer cells. Find out more about how chemotherapy works How do you have cisplatin? You have cisplatin as a drip into your bloodstream (intravenously). Into your bloodstream You might have treatment through a long plastic tube that goes into a large vein in your chest. WebTo further confirm that CYP1B1 is the executor of the UCA1/miR-513a-3p/CYP1B1 molecular axis regulating GC cell apoptosis induced by cisplatin, we simultaneously …
WebSep 5, 2011 · Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma. Clin Cancer Res 15: 1645–1654.
WebLTTs minimise cisplatin-induced DNA damage and evade apoptosis by increased expression of anti-apoptotic factors. The observed diversity among the four LTTs … grants for medical treatmentWebNational Center for Biotechnology Information grants for medicareWebAbstract Cisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. ... grants for mental health agencyWebIt has been reported that cisplatin upregulates the expression levels of Trail, initiator caspase 8, and effector caspase 3, leading to apoptosis in hES [14]. The upregulation of p53, caspase... grants for mental health careWebThe manuscript by Bernardo-Bermejo analyses the metabolic differences between apoptotic bodies released by HK-2 cells, upon induction to apoptosis either by cisplatin or UV light. Although the topic may be potentially of interest, the manuscript is unclear, as well as the main findings. In addition, some methodological issues need to be addressed. chip michaud homologyWebAbstract Cisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. ... adenocarcinoma promotes proliferation via the accumulation of β-catenin 17 and regulates lung tumorigenesis through cell apoptosis and autophagy pathways. 16 USP14 is critical ... chip mexicoWebJan 6, 2024 · Cisplatin is a mainstay of systemic therapy for a variety of cancers, such as lung cancer, head and neck cancer, and ovarian cancer. However, resistance to cisplatin represents one of the most significant barriers for patient outcome improvement. grants for mental health projects canada